Friday, September 23, 2011
Westminster College senior molecular biology major Katie Sinagoga received an undergraduate research grant from Westminster's Drinko Center for Excellence in Teaching and Learning.
Sinagoga's research, "RNAi Suppression of sarA in Staphylococcus aureus, a Regulatory Mechanism for Expression of the Ica Operon and Biofilm Formation," is conducted under the supervision of Dr. Joshua Corrette-Bennett, associate professor and chair of Westminster's Department of Biology, and is the culmination of her four years in Westminster's All-College Honors Program.
Staphylococcus aureus is a bacterium that is fairly harmless on human skin but can become a serious, even deadly, health concern if it enters the body. The protective coating on the bacterium, also known as a biofilm, helps the bacterium evade the immune system and reduces the efficacy of many antibiotics.
Sinagoga's project is trying to determine whether small pieces of DNA and RNA can be used to turn off synthesis of the biofilm, making the bacterium more susceptible to standard antibiotics.
"Katie is an exceptional student with an outstanding work ethic and an innate aptitude for scientific inquiry," Corrette-Bennett said.
Prior research by Westminster molecular biology graduates Emily Fink (2010) and Peter Um (2006) was used to master techniques and gather knowledge about the bacterium and the process of suppression.
Sinagoga is a daughter of John and MaryBeth Sinagoga of Imperial and a graduate of West Allegheny High School.
Contact Corrette-Bennett at (724) 946-7208 or email for additional information.
About Westminster College...
Founded in 1852 and related to the Presbyterian Church (U.S.A.), Westminster College ranks first in the nation as "Best College for Women in Science, Technology, Engineering and Math," according to Forbes.com. Westminster, a top-tier liberal arts college, ranks third in graduation rate performance, according to U.S. News Best Colleges guide. Westminster ranked 6th among liberal arts colleges in social mobility, according to the Washington Monthly College Guide, and is one of the most affordable national liberal arts colleges in Pennsylvania. Westminster is also honored as one of "The Best 376 Colleges" by The Princeton Review, and is named to the President's Honor Roll for excellence in service learning.
Nearly 1,600 undergraduate and graduate students benefit from individualized attention from dedicated faculty while choosing from 42 majors and nearly 100 organizations on the New Wilmington, Pa., campus. Visit www.westminster.edu/advantage to view "Advantage: Westminster" A Strategic Plan 2010-2020.